From Papers to Living Cells
Explore calibrated microscopy, multi-channel fluorophore staining, and quantitative morphology across verified oncology specimens. Every image is grounded in peer-reviewed literature and open-access provenance.
Cancer-Associated Fibroblast
Cancer-associated fibroblasts (CAFs) are prominent stromal cells in solid tumors. Upon activation by tumor-derived TGF-beta, CAFs undergo contractile transdifferentiation, produce dense collagenous extracellular matrix, and secrete immunosuppressive chemokines including CXCL12 (SDF-1) to exclude cytotoxic T lymphocytes from the tumor core.
U2OS Osteosarcoma
U2OS is a human osteosarcoma cell line extensively used in high-content screening and cellular morphology profiling. Cells maintain wild-type p53 and represent an established standard for high-throughput nuclear segmentation and phenotypic screening.
Mouse Stem Cell (Oct4-GFP)
GOWT1 mouse embryonic stem cells express an Oct4-GFP reporter transgene. This standard time-lapse microscopy dataset from the Cell Tracking Challenge enables rigorous evaluation of cell division, nuclear morphology dynamics, and directional motility.